isoniazid will improve the level or effect of pazopanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Prevent coadministration of pazopanib with potent CYP3A4 inhibitors if possible; if need to coadminister, minimize pazopanib dose to 400 mg/day If coadministratio

g. IPF and scleroderma), nevertheless the pathophysiology of such products, relying on immediate administration of drug to tissue, differs drastically from medical bleomycin?induced lung fibrosis. Alternatively, systemic administration of a pro?fibrotic drug like bleomycin ought to much more closely

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